FAQ’s on SVF Stem Cell Treatment in Phoenix and Scottsdale AZ
Stem cell therapy is a form of regenerative medicine that has shown promise in many clinical studies.Stem cells are used to heal, repair, and regenerate damaged, injured, and degenerated tissues, tendons, ligaments, and other body structures.
What types of stem cell therapy are used?
R3 Stem Cell maintains several Centers of Excellence in Phoenix metro, which offer regenerative therapies regularly to patients in need. Many conditions are treated which can be seen HERE. The source of stem cells include both amniotic and umbilical cord tissue, which is obtained ethically and in accordance with FDA regulations.
What are the components of adipose tissue?
Stromal vascular fraction (SVF) is the mononuclear fraction of adipose tissue. This is stem cells that differentiate into pre-adipocytes and functional adipose tissue. SVF contains large numbers of stem cells. Components of the adipose tissue include:
Endothelial progenitor cells – These are endothelial precursor cells that arise from visceral or subcutaneous adipose tissue.
Immune regulatory monocytes and macrophages – These cells have immunological properties. Adipocytes are capable of inducing TNF-alpha secretion from macrophage cells.
Treg (T) regulatory cells – T cells put of signals that lead to immune suppressive activity.
More info on specific stem cell conditions:
Stem Cell Therapy for Arthritis
Stem Cell Therapy for COPD
Stem Cell Therapy for Neurologic Diseases
Stem Cell Therapy for Autoimmune Diseases
Can stem cell therapy treat autoimmune diseases?
According to research, adipose-derived stem cells are being used to treat autoimmune diseases. The body has an immune response that causes destruction of tissues. Stem cells inhibit innate immune activation which can lead to tissue damage. This works by blocking of dendritic cell activity, suppression of macrophage activation, and production of interleukin-1 receptor antagonist cells. While offering regenerative abilities, MSCs can inhibit the immune response.
Does stem cell therapy work for neurological diseases?
The therapeutic effects of MSCs has been demonstrated in both animal and human studies. In a recent study, intrathecal injections of stem cells were used in multiple sclerosis patients. All but one patient had improvement following the injections. In a case study, stem cell therapy was found to offer significant decrease in pain in a patient who had severe multiple sclerosis. In another case study, the patient reported improvement in coordination and balance, as well as improved mood and energy level.
Can SVF stem cell therapy treat arthritis?
In a study involving 61 joints, patients were treated with stem cell injections. At the 6-week follow-up, 100% of the patients improved. Regardless of the arthritis severity, all patients who received stem cell therapy improved.
How are adipose stem cells removed from the patient’s body?
Adipose stem cells are obtained through liposuction. The patient’s abdomen is cleaned using an antiseptic solution. After numbing the skin and deeper tissues with lidocaine (an anesthetic), a small incision is made. A special cannula is inserted to dislodge the fat tissue, which is gently suctioned into a collection device. The fat tissue is a thick, yellow substance, which contains stem cells.
How are the stem cells separated from the fat tissue?
The fatty solution is placed in tubes, which are spun (centrifugation) in the laboratory. The adipocytes and other fat tissue substances are separated from the stem cells in this process. The result yields material with extremely high cell counts.
What are the benefits of using adipose-derived SVF?
Adipose stem cell SVF yields a heterogeneous population of cells that include progenitor cells and stem cells. The SVF cells transcribe many genes that are implicated in tissue repair, inflammation, and angiogenesis. Benefits of SVF include ease of obtaining the cells, more stem cells compared to bone marrow-derived stem cells, and stronger angiogenic and regenerative potential.
Riordan NH, Ichim TE, Min WP, et al. (2009). Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis. Journal of Translational Medicine, 7(29).
Tantuway V, Johar SAM, Rassiwala M, et al. (2016). Use of autologous adipose tissue derived stromal vascular fraction in treatment of knee osteoarthritis and chondral lesions. Journal of Evidence Based Medicine & Healthcare.